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BCG vaccination provides incomplete protection against tuberculosis in infants. A new vaccine, modified Vaccinia Ankara virus expressing antigen 85A ( MVA85A ), was designed to enhance the protective ...


A vaccine for enterovirus 71 ( EV71 ) is needed to address the high burden of disease associated with infection. Researchers have assessed the efficacy, safety, immunogenicity, antibody persistence, a ...


A safe and effective vaccine for the prevention of human immunodeficiency virus type 1 ( HIV-1 ) infection is a global priority.Researchers have tested the efficacy of a DNA prime-recombinant adenovir ...


The influenza A(H1N1) 2009 monovalent vaccination programme was the largest mass vaccination initiative in recent US history. Commensurate with the size and scope of the vaccination programme, a proje ...


The candidate malaria vaccine RTS,S/AS01E has entered phase 3 trials, but data on long-term outcomes are limited.For 4 years, researchers followed children who had been randomly assigned, at 5 to 17 m ...


During the 2009 influenza A (H1N1) pandemic, pregnant women were at risk for severe influenza illness. This concern was complicated by questions about vaccine safety in pregnant women that were raised ...


A new study is helping to provide a better understanding of vaccines for whooping cough, the common name for the disease pertussis. Based on an animal model, the study conducted by the FDA ( Food and ...


The Committee for Medicinal Products for Human Use ( CHMP ) has finalised its assessment of an application to extend the use of Menveo to infants aged 2 to 23 months. The CHMP did not consider the res ...


Acellular pertussis vaccines effectively prevent pertussis in vaccinated individuals, but may fail to prevent colonization and transmission to uninfected individuals, according to a study. Acellular v ...


Initial vaccinations for human papillomavirus ( HPV ) at a young age is important for maximizing quadrivalent HPV vaccine effectiveness according to a Swedish study.HPV vaccination programs have been ...


Numerous studies have shown that inflammation has a relevant role in the pathogenesis of atherosclerosis as well as of acute coronary syndromes. Moreover, markers of inflammation predict cardiovascul ...


Inflammation, platelet reactivity and cardiac autonomic dysfunction increase the risk of cardiovascular events, but the relationships between these prognostic markers are poorly defined. In a stud ...


The FDA ( Food and Drug Administration ) and CDC ( Centers for Disease Control and Prevention ) routinely monitor the safety of all U.S. vaccines by using several vaccine safety surveillance systems, ...


The FDA ( Food and Drug Administration ) has approved the vaccine Gardasil for the prevention of anal cancer and associated precancerous lesions due to human papillomavirus ( HPV ) types 6, 11, 16, an ...


An experimental vaccine intended to prevent genital herpes disease in women, although generally safe and well-tolerated, proved ineffective when tested in the recently concluded clinical study known a ...